TNF, JAK Inhibitors CV Safety Compared in PsA, AxSpA

CLEVELAND – Patients with axial spondyloarthritis or psoriatic arthritis who used Janus kinase (JAK) inhibitors did not have higher risk of myocardial infarction, stroke, or venous thromboembolism (VTE), compared with those who used tumor necrosis factor inhibitors (TNFi), according to new research. The information was presented in a poster at the annual meeting of the Spondyloarthritis Research and Treatment Network (SPARTAN). […]

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Valbenazine improves chorea associated with Huntington's disease

The drug valbenazine statistically improves chorea, a movement disorder commonly associated with Huntington's disease, when compared to a placebo, according to a recent international study led by UTHealth Houston researcher Erin Furr Stimming, MD, who served as principal investigator on behalf of the KINECT-HD Huntington Study Group. The study results – which were published online today and will appear in […]

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Cones in retinal degeneration may retain visual function

Cone photoreceptors in retinal degeneration have been thought to be dormant However, new research suggests cone photoreceptors in a degenerating retina may continue producing responses to light. Researchers recorded downstream signals from the retina that indicate visual processing was not as compromised as might be expected. In the retina, the cells responsible for the visual experience are rods and cones. […]

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Mechanical thrombectomy significantly improves patient outcomes and quality of life following a pulmonary embolism

The proportion of patients with normal echocardiographic RV function increased from 15.1% pre-thrombectomy to 95.1% and 94% had normal pulmonary artery pressures. All-cause mortality was 0.3% at the 48-hr visit, 0.8% at the 30-day visit, and 4.6% at study exit (median = 199 days post-treatment). Patient exercise tolerance and symptoms also improved significantly after treatment. The distance a patient can […]

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Study Says Casual Pot Use Harmful to Teens

Recreational marijuana use by teenagers isn’t as harmless as many people seem to think, even as it becomes increasingly legal in this country, authors of a new study say. Teenagers who use cannabis recreationally are 2 to 3 times more likely to have depression and suicidal thoughts than those who don’t use it. And teens who have cannabis use disorder […]

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Are higher blood pressure, glucose, and low-density lipoprotein cholesterol in stroke survivors associated with cognitive decline?

In a recent study published in the JAMA Network Open, researchers analyzed individual participant data of 982 adult stroke survivors aged ≥18 years from four cohort studies conducted in the United States between 1971 and 2019. The study aimed to assess whether their higher systolic blood pressure (SBP), glucose, and low-density lipoprotein (LDL) cholesterol levels post-stroke accelerated their cognitive decline. […]

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Physical activity level inversely linked to Parkinsons disease in women

In women, a higher physical activity (PA) level is associated with a lower incidence of Parkinson’s disease (PD), according to a study published online May 17 in Neurology. Berta Portugal, Ph.D., from Université Paris-Saclay, and colleagues examined the association between time-varying PA and PD using lagged analyses to address the potential for reverse causation. Data were obtained from the E3N […]

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