New computational tool identifies novel targets for cancer immunotherapy

Researchers at Children’s Hospital of Philadelphia (CHOP) and the University of California, Los Angeles (UCLA) have developed a computational platform capable of discovering tumor antigens derived from alternative RNA splicing, expanding the pool of cancer immunotherapy targets. The tool, called “Isoform peptides from RNA splicing for Immunotherapy target Screening” (IRIS), was described in a paper published May 16 in the […]

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Cancer: Could daily vitamin D help lower risk of death?

Millions of people die from different types of cancer every year. Researchers from the German Cancer Research Center say daily intake of vitamin D could help reduce cancer death risk by 12%. Scientists found that taking vitamin D daily was especially beneficial for people ages 70 and older, and in those who started taking supplements before receiving a cancer diagnosis. […]

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Grim poster begs medics to stop smearing their bogies on walls

Grim NHS poster begs medics to stop smearing their bogies on walls (and wiping their bums with other people’s coats!) Hospital matrons are threatening the offenders with ‘disciplinary proceedings’ Medics have been told to stop wiping their bogies on walls — or face ‘disciplinary proceedings’. The grim warning, printed out and seemingly stuck on a toilet door, was posted to social […]

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"Smart" sutures can detect inflammation and release drugs

Inspired by sutures developed thousands of years ago, MIT engineers have designed "smart" sutures that can not only hold tissue in place, but also detect inflammation and release drugs. The new sutures are derived from animal tissue, similar to the "catgut" sutures first used by the ancient Romans. In a modern twist, the MIT team coated the sutures with hydrogels […]

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Patient ­plea to Steve Barclay to “please save my life” for new liver

A cystic fibrosis patient is ­begging Health Secretary Steve Barclay to “please save my life” after waiting 14 times longer than average for a new liver. Sarah Meredith, 30, joined the transplant list in 2021 with a failing liver, yet complex Transplant Benefit Score algorithms penalise young patients like her, with genetic-linked rare forms of liver disease. Her family claim […]

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The different types of depression, explained

An estimated 5% of adults worldwide suffer from depression, according to the World Health Organization (WHO). This mental health disorder permeates all areas of life from personal relationships to academic and professional ones and goes well beyond typical mood fluctuations and everyday concerns. Depression can affect anyone, but individuals who have experienced trauma, significant losses or high stress levels are […]

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