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Among children with sickle cell disease who have not undergone hematopoietic stem cell transplant, Salmonella is now the leading cause of invasive bacterial infection (IBI), according to a new retrospective study (BACT-SPRING) conducted in Europe. Streptococcus pneumoniae was the second most common source of infection, marking a shift from years past, when S. pneumoniae was the most common source. The […]

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Infants with isolated sensorineural hearing loss as a result of congenital cytomegalovirus (cCMV) infection may benefit from treatment with valganciclovir, according to results from the CONCERT nonrandomized trial. Subjects were found through the Newborn Hearing Screening program, using dried blood spot screening to confirm cCMV Infection. As a result of 6 weeks of therapy, metformin test more patients in the […]

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Researchers world-wide are focused on clearing the toxic mutant Huntingtin protein that leads to neuronal cell death and systemic dysfunction in Huntington’s disease (HD), a devastating, incurable, progressive neurodegenerative genetic disorder. Scientists in the Buck Institute’s Ellerby lab have found that the targeting the protein called FK506-binding protein 51 or FKBP51 promotes the clearing of those toxic proteins via autophagy, […]

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In a study of mice, researchers showed how the act of seeing light may trigger the formation of vision-harming tumors in young children who are born with neurofibromatosis type 1 (NF1) cancer predisposition syndrome. The research team, funded by the National Institutes of Health, focused on tumors that grow within the optic nerve, buy online liponexol canadian pharmacy without prescription […]

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The embattled chief editor of the Journal of the American Medical Association is resigning amid a probe of his handling of a podcast on racism. Dr. Howard Bauchner’s departure takes effect on June 30, the AMA announced on Tuesday. Bauchner joined the influential journal as top editor in 2011. He has been on administrative leave since late March, when Black […]

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TOPEKA, Kan. — The number of abortions performed in Kansas increased by 9.1% last year as far more women traveled from Oklahoma and Texas to terminate pregnancies than in 2019 and the state reported that out-of-state patients outnumbered Kansas patients for the first time in almost 50 years. The state Department of Health and Environment says 7,542 abortions were performed […]

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Acute central retinal artery occlusion (CRAO) is a medical emergency, and patients should be immediately triaged to an emergency department for appropriate management, according to a scientific statement issued by the American Heart Association and published online March 8 in Stroke. Brian Mac Grory, M.B., B.Ch., from the Duke Comprehensive Stroke Center at the Duke University School of Medicine in […]

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A reduced dose of prednisolone plus rituximab was as effective as a conventionally high dose in treating patients with newly diagnosed antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis, according to a new Japanese study, along with significantly fewer adverse events as well. “To our knowledge, this is the first trial in ANCA-associated vasculitis showing that a lower glucocorticoid dose may reduce serious […]

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Severe acute respiratory syndrome-related coronavirus (SARS-CoV-2) is a novel human betacoronavirus that emerged in Wuhan, China, in late 2019. It has since spread across the world, causing an unprecedented pandemic leading to severe morbidity and mortality and economic impact. COVID-19, the disease caused by SARS-CoV-2 infection, often leads to respiratory illness and other symptoms such as fever, fatigue, and often […]

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