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Gut bacteria linked to mental health, other chronic disease risks among NHPI populations

  • A novel interaction between self-esteem and abundance of Veillonellaceae bacteria, where increased levels of this bacteria in the gut corresponded to a significant increase in self-esteem, with individuals with low self-esteem (a risk factor for depression) showing abnormally low levels of this bacteria.
  • Shared imbalance of Bacteroidetes between diabetes and obesity, where its abundance was observed to decrease with poor glycemic control and increase with obesity.
  • A significant and specific deficiency in the levels of butyrate-producing bacteria in the gut of pre- and diabetic participants, that corresponded to increased systemic inflammation.
  • A novel significant association between the levels of Cyanobacteria (which produces toxins and implicated in cancer risk in Hawai’i) and poor glycemic control, with overabundance of this bacteria in the gut of diabetic participants.
  • A significantly higher gut microbial diversity in obese and diabetic individuals of NHPI ancestry. This contrasts with the relationship observed between obesity and diabetes in other ethnic/race groups previously reported in other studies.

Preventing chronic diseases among NHPIs

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