New health research suggests novel combination therapy for triple-negative breast cancer

Research led by Suresh Alahari, Ph.D., Professor of Biochemistry at LSU Health New Orleans schools of Medicine and Graduate Studies, suggests a combination of drugs already approved by the FDA for other cancers may be effective in treating chemo-resistant triple-negative breast cancer. The results are published in Molecular Cancer. Triple-negative breast cancer (TNBC) tumors lack estrogen receptors, progesterone receptors, and […]

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Immune cells anchored in tissues offer unique defenses against pathogens and cancers

Scientists exploring how our immune system responds to pathogens and cancers have ramped up their attention to CD8+ T cells, which are deployed in response to infections and malignancies and equipped to remember the identities of malicious invaders. While some of these critical “memory” cells circulate throughout the body, others are known to remain lodged within bodily organs to guard […]

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COVID-19 vaccines saved 20 million lives in 1 year

A new study estimates that COVID-19 vaccines helped avert 19.8 million deaths across the globe during the first year after vaccination campaigns were initiated. The study found that vaccine inequity resulted in a disproportionately higher number of deaths prevented by vaccination in high-income nations than in lower-income nations. Several low-income nations failed to meet the World Health Organization (WHO) target […]

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Primary Hyperparathyroidism Raises Fracture, CV Risk

Dr Mattias Lorentzon Patients with untreated primary hyperparathyroidism show significant increases in the risk of hip fracture, cardiovascular events, and mortality, however, the risk is reduced when treated with parathyroidectomy, results from a large sample of patients in Sweden show. “Our results indicate that the risk of these severe outcomes is lower after surgery than before, suggesting a clinical benefit from […]

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Smoking promotes development of severe pulmonary hypertension

About 1% of the world’s adult population suffers from pulmonary hypertension (PH). Among the many forms of this disease is idiopathic pulmonary arterial hypertension (IPAH), a rare but very severe disease. The term “idiopathic” means that there is no tangible cause for the disease. A study group led by the Department of Pneumology at the Hannover Medical School (MHH) has […]

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Study: Nearly 80% of people in the U.S. have low to moderate cardiovascular health

About 80% of people in the U.S. have low to moderate cardiovascular health based on the American Heart Association's new Life's Essential 8™ checklist according to a new study published today in Circulation, the Association's flagship, peer-reviewed journal. Life's Essential 8™, also published today in Circulation, details the Association's updated guidance to measure cardiovascular health, adding healthy sleep as essential […]

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