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<img class="aligncenter" src="https://scx1.b-cdn.net/csz/news/800a/2023/research-challenges-tr.jpg"
alt="Research challenges traditional theory of mechanisms of cocaine self-administration"
title="The cumulative record of injections (A), active lever presses (B), and the calculated levels of cocaine at the time of each event (C) during a representative session. Once rats acquired self-administration behavior on FR50 schedule, rats were on FR1/FR50 sessions in which the unit dose was one of 0.1, does low testosterone affect facial hair growth 0.3, 0.5, 0.75, 1.5 and 3 µmol/kg, and the number of injections allowed for each FR phase was 225, 75, 60, 50, 25 and 15 respectively. This figure shows a representative FR1/FR50 session at 1.5 µmol/kg cocaine unit dose. After 4 loading injections of the standard loading dose (1.5 µmol/kg), 25 unit doses were administered for each schedule, and the rat displayed regular cocaine self-administration on each schedule. After access to cocaine was terminated, active lever presses had no consequence but were recorded until lever pressing stopped. Credit: Scientific Reports (2023). DOI: 10.1038/s41598-023-43506-y” width=”800″ height=”529″>
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