In November 2021, Stuart had an appointment at Specsavers in Bridgnorth, Shropshire. Seen by ophthalmologist Teresa Highes, Stuart’s eye had a colouring that caught the eye specialist off guard. “Typically, the retina is orange-red in colour but, just off to the side, I could see a very dark grey area,” Highes said. “In order to take a closer look at […]

Children who are breastfed for longer appear to be more likely to gain slightly better results in their school GSCEs at age 16 compared with non-breastfed children, suggests a study published online in the journal Archives of Disease in Childhood. The evidence of improved educational outcomes is still apparent even when various factors are taken into account such as people's […]

If you’re actually trying to get pregnant, the time period you have to wait after ovulation to see if things, well, worked can feel like months. Conversely, if you’re on the missed period and panicking train, there is nothing more nerve-wracking than the few minutes you wait for an at-home pregnancy test result to appear. The reality is, even though […]

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Skin cancer can pop up anywhere on your skin, including the soles of your feet and even under your fingernails. That’s what happened to Isabel Lievano, who was diagnosed with melanoma when her dermatologist determined that a persistent black spot under her fingernail was the deadliest form of skin cancer. Lievano, 69, lost her nail, but not her finger or […]

Northwestern Medicine investigators have discovered that the overexpression of a transcription factor prevented bone loss in mouse models of chronic kidney disease, according to a recent study published in the Journal of Clinical Investigation. The findings demonstrate that the transcription factor hepatocyte nuclear factor 4 alpha (HNF4α) regulates bone frailty and is implicated in the development of renal osteodystrophy (ROD), […]

Researchers at the Faculty of Medicine at the University of Freiburg have gained significant new insights into metabolic processes in the kidney. The scientists from the Institute of Genetic Epidemiology at the Medical Center—University of Freiburg measured tiny molecules, so-called metabolites, which occur in blood and urine and reflect our metabolism, in samples from more than 5,000 study participants. They […]

Across patients’ age groups, adding the immune checkpoint inhibitor nivolumab to chemotherapy significantly improves progression-free survival in advanced stage Hodgkin lymphoma while also reducing toxicities, making it a new standard of care, compared with the CD30-targeting drug brentuximab vedotin. “[SWOG] S1826, the largest Hodgkin lymphoma study in National Clinical Trials Network history, is a key step toward harmonizing the pediatric […]

A treatment that involves genetically modifying the body’s own immune cells has been found to cut the risk of disease progression by 74 percent in people with a rare type of blood cancer, results showed Monday. Ciltacabtagene autoleucel—also known by its trade name Carvykti—was tested in a clinical trial involving 419 patients with multiple myeloma, whose disease was not responsive […]

MILAN — Treatment of rheumatoid arthritis (RA) with tumor necrosis factor inhibitors (TNFi) does not appear to demonstrate a consistent and significant risk for demyelinating disease, according to a systematic literature review presented at the European Alliance of Associations for Rheumatology (EULAR) 2023 Annual Meeting. Dr Isabel Castrejon The review was conducted by Isabel Castrejon, MD, of the rheumatology department […]