Reviewed Regenstrief Institute research scientist Matthew J. Bair, M.D., M.S., and the Indiana Institute of Medical Research (IIMR) at Richard L. Roudebush VA Medical Center have been awarded the Creative Forces®: National Endowment for the Arts Military Healing Arts Network Award for Clinical Study of Music Therapy and Chronic Pain in U.S. Veterans. The research project titled "Stepped-Care Intervention of […]

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Photo: Cleveland Clinic The Wellcome Trust has selected the Cleveland Clinic-IBM Discovery Accelerator to develop proof-of-concept demonstrations of quantum computing for biologic and health applications through the Wellcome Leap Quantum for Bio Challenge. WHY IT MATTERS Q4Bio by Wellcome Leap, a U.S.- based nonprofit organization aiming to accelerate and increase the number of breakthroughs in global health, seeks to codevelop […]

In a recent study published in JAMA Neurology, researchers investigated whether slow-wave sleep (SWS) proportions reduced as individuals aged and whether intra-individual decreases were linked to dementia risk. Study: Association Between Slow-Wave Sleep Loss and Incident Dementia. Image Credit: Ground Picture/Shutterstock.com Background Inadequate sleep might be a risk factor for dementia. Sleep deprivation, in particular, stimulates the amyloid buildup and […]

In a recent article published in the journal Development, researchers investigate the role of the ACTL7B gene in sperm formation using Actl7b-deficient mice. Study: Actl7b deficiency leads to mislocalization of LC8 type dynein light chains and disruption of murine spermatogenesis. Image Credit: Komsan Loonprom / Shutterstock.com Background ACTL7B, a testis-specific actin-related protein (Arp), shares up to 60% amino acid identity with conventional actins and is highly […]

Reviewed A new drug developed by professors from the School of Pharmacy and Pharmaceutical Sciences at Binghamton University has received Food and Drug Administration (FDA) approval for the treatment of patients with Duchenne muscular dystrophy (DMD), a common genetic disease that mostly affects young boys. DMD is the most common genetic disease. It leads to the loss of the dystrophin […]

The immune system is a crucial part of our survival, regularly fending off wide-ranging attacks on the body, both internal and external. Unsurprisingly, the elegant defense system that protects us from viruses, bacterial infections, cancer, and other threats is immensely complicated. Each time it mounts a response, it must quickly and carefully orchestrate communication across vast numbers of cells and […]

Symptoms of debilitating bone disease osteoporosis explained Helen Leigh first started to realise that something was wrong when she was pregnant with her daughter at 31. “I developed back pain, which I had intermittently for ten years,” the 56-year-old said.  However, it wasn’t until much later that she got a diagnosis. When she was 42, a “bad” skiing injury left […]

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According to a new paper in Rheumatology, published by Oxford University Press, JAK inhibitors, which doctors have used to treat patients with arthritis despite concerns about the effectiveness of such drugs, actually do work quite well. In a multicenter, retrospective study Japanese researchers found that the drugs resulted in impressive remission rates in patients, most of whom choose to continue […]