A new editorial paper was published in Oncotarget, titled “GBP3-STING interaction in glioblastoma coordinates autophagy, anti-oxidative, and DNA repair programs in response to temozolomide.” In their recent editorial, researchers Jun Ma, Ziyu Wang, Clark C. Chen, and Ming Li from the University of Minnesota discussed the methylating agent, Temozolomide (TMZ). TMZ is the standard adjuvant chemotherapeutic drug for glioblastoma, which […]

Snoring: Doctor explains how to sleep better at night Almost half of Britons are guilty when it comes to snoring at night. While it is typically beyond our control, it can be extremely frustrating for anyone you’re sharing a bed with. While it can be a sign of something more serious, like sleep apnoea, it can also be linked to […]

Fake injection pens of Ozempic, a hugely popular diabetes drug that went viral on social media as a way to lose weight, are circulating in Europe, drug authorities have warned. Ozempic, which involves a once-weekly injection from a pre-filled pen, was originally developed to treat type 2 diabetes. However since it became clear the drug was effective for weight loss, […]

Source: Read Full Article

A research collaboration led by the University of Chinese Academy of Sciences, China, investigated the role of CHIT1, a protein associated with microglia, in aging. In a paper, “CHIT1-positive microglia drive motor neuron aging in the primate spinal cord,” published in Nature, the group identifies distinct states of microglia in the aged spinal cord associated with aging-related changes. It links […]

Type 1 diabetes is an autoimmune disease that causes the body’s immune system to attack and destroy insulin-producing beta cells in the pancreas. Traditional management of type 1 diabetes has primarily involved replacing the missing insulin with injections which, though effective, can be expensive and burdensome. A new study, published in Cell Reports Medicine, led by researchers at the University […]

Polyenes are among the most commonly used broad-spectrum antifungals but have significant associated renal toxicity. Attempts to develop newer drugs of the same class without these adverse effects led to nothing, mostly because of the perception that their antifungal activity was based on membrane permeabilization. Study: Tuning sterol extraction kinetics yields a renal-sparing polyene antifungal. Image Credit: Fahroni/Shutterstock.com Amphotericin B […]

By Keynote ContributorCrystal Girod Senior Product ManagerBeckman Coulter Life Sciences Written by Keynote Contributor, Crystal Girod, Senior Product Manager at Beckman Coulter Life Sciences.  Proteomics is the area of research that studies protein expression, interactions, function, structure, and post-translational modifications. It can detect and quantify all the modifications and complex interactions of the proteins within a sample, which means this technique holds […]

Researchers at Weill Cornell Medicine have uncovered a novel route to stimulate the growth of healthy insulin-producing pancreatic beta cells in a preclinical model of diabetes. The findings hold promise for future therapeutics that will improve the lives of individuals with type 2 diabetes—a condition that affects more than half a billion people worldwide. This study, published in the Journal […]

I’m a psychologist – here’s how to tell if your child has ADHD or if they’re just a livewire It can be tricky for parents to know whether their child is among 5% with ADHD While often linked to ‘disruptive’ and ‘naughty’ behaviour, it is far more complex ADHD awareness and diagnoses are on the rise. But it can still be […]