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The investigational anti-amyloid drug donanemab (Eli Lilly) has similar clinical efficacy in apolipoprotein E ε4 (APOE4) heterozygous and homozygous carriers and noncarriers at high risk of Alzheimer’s disease (AD), new data from the TRAILBLAZER-ALZ 2 study show. “It’s important to understand whether APOE genotype affects rates of clinical decline in our clinical trial populations and if it affects efficacy of amyloid-targeting […]

An international team has for the first time researched the longevity of neutralizing antibodies in HIV-1-infected people. Currently, it is assumed that an HIV-1 vaccine can only be effective if it produces these antibodies in vaccinated humans. The findings improve understanding of the dynamics of such antibodies and are an important building block for further research into an HIV-1 vaccine. […]

A study of more than 73,000 primary care physicians (PCPs) and nurse practitioners (NPs) suggest that both are similarly likely to inappropriately prescribe medications to older patients. According to the authors, this study adds to growing evidence indicating that when prescriptive authority is expanded to include NPs, these new prescribers do not perform worse than physicians. The study is published […]

A new study, published in the European Heart Journal, is the first to assess how different movement patterns throughout the 24-hour day are linked to heart health. It is the first evidence to emerge from the international Prospective Physical Activity, Sitting and Sleep (ProPASS) consortium. Cardiovascular disease, which refers to all diseases of the heart and circulation, is the number […]

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Dior’s new baby skincare line features $230 perfume water that could trigger skin problems in young children, experts warn The products contain ‘fragrance’, which ‘could be anything’ said a cosmetologist Dr Kazlouskaya added that even natural extracts could trigger adverse reactions READ MORE: Mom makes soaps and creams from breast milk and SELLS them The luxury fashion house Dior is best-known […]

The Biden administration is encouraging schools throughout the United States to carry naloxone to help prevent fatal drug overdoses in students. The medication (Narcan) was approved earlier this year as an over-the-counter (OTC) nasal spray. Faculty and students should be prepared to use it to help others, Dr. Rahul Gupta, director of the White House Office of Drug Control Policy, […]

A new study finds that shooting survivors may not seek the mental health services they need after experiencing gun violence due to stigma, fear and a lack of trusted resources. The study, led by assistant professor Lauren Magee with the Indiana University O’Neill School of Public and Environmental Affairs in Indianapolis, is featured in the JAMA Network Open. Magee and […]

After enduring a difficult pregnancy marred with severe bouts of nausea and vomiting, Christina Roberto recalls the overwhelming sense of relief she felt two years ago when she finally brought her newborn daughter, Charlotte, safely home from the hospital. “It was a really stressful pregnancy,” she said. “So there was this relief I felt getting home with Charlotte—and thinking everyone’s […]