Regulating immunological memory may help immune system fight disease, study finds

Scientists have long sought to better understand the human body’s immune responses that occur during various diseases, including cancer and inflammatory diseases. In a recent study at the University of Missouri, Emma Teixeiro, an associate professor in the MU School of Medicine, and her team analyzed how immunological memory—the memory the body’s immune system retains after an infection or vaccination […]

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Role of lymphatic system in bone healing revealed

It was previously assumed that bones lacked lymphatic vessels, but new research from the MRC Human Immunology Unit at Oxford’s MRC Weatherall Institute for Molecular Medicine not only locates them within bone tissue, but demonstrates their role in bone and blood cell regeneration and reveals changes associated with aging. The lymphatic system is a network of vessels that branch out […]

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Report outlines national plan to test wastewater for harmful germs

The pandemic brought the utility of testing wastewater to gauge viral spread to the fore. Now, experts at the independent National Academies of Sciences (NAS) have issued a report outlining a roadmap for the broader surveillance of Americans’ wastewater. The report “reviews the usefulness of community-level wastewater surveillance during the pandemic and assesses its potential value for control and prevention […]

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FDA OKs Zanubrutinib (Brukinsa) for CLL or SLL

The US Food and Drug Administration (FDA) granted accelerated approval for zanubrutinib (Brukinsa) to treat patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). The approval for the second-generation Bruton’s tyrosine kinase (BTK) inhibitor expands on the drug’s previous approvals for mantle cell and marginal zone lymphoma. “We have seen striking data from the BRUKINSA development program demonstrating […]

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Combo of Previous COVID-19 Infection and Vaccination Gives Best Protection

People who have been infected with COVID-19 and vaccinated against it are more likely to avoid serious illness than those who were only previously infected, a new study says. It’s called “hybrid immunity” and it offers better protection from COVID reinfection, according to a study published in The Lancet. The World Health Organization said the study shows “the advantages of […]

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Dieters Don’t Eat as Healthy as They Think They Do

Most would-be dieters don’t change their eating patterns as much as they think they do, and have misconceptions about diet quality, according to researchers at the Harvard T. H. Chan School of Public Health and Massachusetts General Hospital. What to know: Dieters actively try to make healthier choices, but most people overestimate how much change they’ve made to their overall […]

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Bowel cancer mutations that impact immunotherapy identified

A new library documenting hundreds of mutations can help to explain why some cancers don’t respond to immunotherapies, and highlights potential pathways that could be drug targets in the future. The researchers, from the Wellcome Sanger Institute, Open Targets, and collaborators, used CRISPR gene editing technology and mini tumors to understand the role of thousands of mutations in bowel cancer […]

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