Pan-coronavirus vaccine shows success in mouse studies

Reviewed A vaccine designed to protect against three different deadly coronaviruses shows success in mouse studies, demonstrating the viability of a pan-coronavirus vaccine developed by researchers at the Duke Human Vaccine Institute. Publishing in the journal Cell Reports, the single nanoparticle vaccine included components of a previous vaccine that was shown to protect mice and primates against multiple variants of […]

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How our brain deconstructs a world in constant motion

It’s a miracle that people aren’t constantly getting into car accidents. Whizzing by at 65 miles per hour in a car, the brain rapidly decodes millions of photons worth of information from the eyes, and then must use that information to instantly figure out where it is and where it needs to go. Is that a pedestrian approaching the sidewalk […]

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The rise and fall of antibiotics. What would a post-antibiotic world look like?

These days, we don’t think much about being able to access a course of antibiotics to head off an infection. But that wasn’t always the case—antibiotics have been available for less than a century. Before that, patients would die of relatively trivial infections that became more serious. Some serious infections, such as those involving the heart valves, were inevitably fatal. […]

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Antiphospholipid Antibodies Vary by Race in People With SLE

TOPLINE: The prevalence of clinically meaningful levels of antiphospholipid antibodies (aPLs) is significantly lower among Black patients with systemic lupus erythematosus (SLE), compared with people of other races and ethnicities. METHODOLOGY: The researchers reviewed data from seven longitudinal SLE cohorts including more than 2500 individuals to examine the overall prevalence of aPLs as well as their presence by race. Clinically […]

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REBOA Fails to Improve Outcomes in Traumatic Hemorrhage

TOPLINE: For trauma patients with exsanguinating torso hemorrhage, resuscitative endovascular balloon occlusion of the aorta (REBOA) did not reduce mortality, and may have increased 90-day mortality, when added to standard hemorrhagic management in a randomized controlled trial. METHODOLOGY: REBOA is a novel technique whereby a percutaneously inserted balloon is inflated in the aorta. The UK-REBOA trial is the first randomized […]

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Osteoarthritis may be treatable and reversible, new study shows

Reviewed Current osteoarthritis treatment manages symptoms rather than addressing the underlying disease, but a new University of Adelaide study has shown the condition may be treatable and reversible. Osteoarthritis is the degeneration of cartilage and other tissues in joints and is the most common form of arthritis in Australia, with one in five people over the age of 45 having […]

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