Dabrafenib, trametinib found more effective in pediatric glioma with BRAF V600

Dabrafenib plus trametinib results in significantly more responses and longer progression-free survival than standard chemotherapy for pediatric patients with low-grade glioma with BRAF V600 mutations, according to a study published in the Sept. 21 issue of the New England Journal of Medicine. Eric Bouffet, M.D., from The Hospital for Sick Children in Toronto, and colleagues conducted a phase 2 trial […]

» Read more

Q&A: Why are ineffective oral decongestants still on store shelves?

A Food and Drug Administration advisory panel concluded last week that the decongestant phenylephrine, contained in many over-the-counter cold remedies—including some formulations of popular brands like Sudafed, Tylenol, and Nyquil—is ineffective when taken orally. The finding potentially upsets a significant part of the over-the-counter market for cold and flu remedies as summer fades, and the cold and flu season approaches. […]

» Read more

Bindi Irwin’s Daughter Grace Spots a Wild Animal That Takes Us Straight Back to Our Childhoods

After-school cartoons were one of the highlights of childhood, and PBS Kids had all the best shows. In the ‘90s, my siblings and I could spend hours watching Zoom, Wishbone, Arthur, and more, while snacking on Fruit Roll-Ups and drinking cherry Kool-Aid. It’s been a while since I’ve thought about those fond memories, but Bindi Irwin’s latest post with her […]

» Read more

Time for Personalized Radiation Therapy in Lung Cancer?

TOPLINE: Individualized stereotactic ablative radiotherapy (SABR) based on lung tumor volume, location, and histology yielded high local control and low toxic effects, according to findings from a phase 2 study. METHODOLOGY: SABR is commonly used to treat lung tumors but can come with severe toxicities. Researchers conducted a single-arm, nonrandomized phase 2 trial, involving 217 unique patients with 285 lung […]

» Read more
1 47 48 49 50 51 1,330