Reviewers’ Notes Scientific research requires patience. The rewards are not always immediate, and the technology needed does not always exist. Michael A. Trakselis, Ph.D., professor and director of graduate affairs for the Department of Chemistry and Biochemistry at Baylor University, understands this. For 15 years, Trakselis has been interested in the MCM8/9 enzyme. Part of the minichromosome maintenance protein (MCM) […]

You can tell a lot about the state of your health by looking at your hands. From how sturdy your nails are, to how easy it is to bend your fingers, there are plenty of warning signs you could be under the weather. Start by doing these five simple checks below – and make sure to see a doctor if […]

Patients with major depressive disorder (MDD) and suicidal behavior during the depressive period have over double the mortality rate of those without a suicide attempt, new research suggests. Investigators studied close to 143,000 patients, encompassing more than 150,000 MDD episodes. Episodes of depression with suicidal behavior (MDD-SB) were compared to MDD episodes without suicidal behavior (MDD-non-SB). Suicidal behavior was associated […]

The CDI team assessed more than 5,000 nasopharyngeal swabs of patients from nine HMH hospitals, from December 2020 to June 2022. The cross-sectional view of this part of the pandemic assessed the de-identified swabs to include variants, vaccination status, clinical outcomes, and underlying risk factors. The scientists essentially tracked the evolution of the virus, especially in the appearance of successive […]

Key bladder cancer genes have been uncovered through studying the cancers in cats and dogs, in a significant stride for finding which of many mutations are the most important in the cancer’s development. Previous research has identified around 60 genes responsible for bladder cancer development in humans—too many to attempt to develop targeted drugs, and current treatment options for patients […]

Are dietary cholesterol and blood cholesterol the same thing? What is dietary cholesterol, then? How much dietary cholesterol can I eat? Does that mean I can eat eggs? What if I have high blood cholesterol? Why has dietary cholesterol advice changed over the years? But it’s settled now, right? Source: Read Full Article

Reviewers’ Notes Intravascular imaging-guided percutaneous coronary intervention (PCI) is associated with a lower rate of target lesion failure compared with angiography-guided PCI, according to late breaking research presented in a Hot Line session today at ESC Congress 2023. Numerous randomized trials have compared intravascular imaging-guided PCI with angiography-guided PCI. However, most of these prior trials have used intravascular ultrasound (IVUS). […]

Researchers at Saint Louis University School of Medicine say diagnostic delays frequently occur in patients with undiagnosed head and neck cancer (HNC) and are calling for improved dissemination of current clinical practice guidelines in a new paper published Aug. 24 in JAMA Otolaryngology—Head & Neck Surgery. Researchers found that undiagnosed HNC patients with neck swelling and other symptoms are frequently […]

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Reviewers’ Notes In iron-deficient patients with heart failure and reduced or mildly reduced left ventricular ejection fraction, intravenous ferric carboxymaltose (FCM) is associated with a reduced risk of the composite outcome of total cardiovascular hospitalization and cardiovascular death through 52 weeks compared with placebo, according to late-breaking research presented in a Hot Line session today at ESC Congress 2023. Iron […]