As we age, strength training and aerobic exercise become increasingly important. Studies have shown strength training may enhance quality of life and improve our ability to do everyday activities, hydrocodone shot in knee while physical inactivity—also known as sedentary behavior—can lead to numerous adverse health conditions and outcomes, including premature death. Aging rural women are at particular risk for physical […]

A new blood test that can identify progression of osteoarthritis in the knee is more accurate than current methods, providing an important tool to advance research and speed discovery of new therapies. The test relies on a biomarker and fills an important void in medical research for a common disease that currently lacks effective treatments. Without a good way to […]

Researchers may have found an unlikely contributor to the development of Alzheimer’s disease: the bacteria in your gut. Their study, published in the journal Science, suggested that certain gut bacteria increase the brain damage seen in mice with an Alzheimer’s-like disease. In Alzheimer’s disease—the most common form of dementia—proteins build up abnormally in the brain. One of these proteins is […]

Researchers published the study covered in this summary on Research Square as a preprint that has not yet been peer reviewed. Key Takeaways There was an inverse relationship between blood levels of thyroid-stimulating hormone (TSH) and free thyroxine (FT4) in patients with various types of cancer, as seen in healthy patients, but the normal reference ranges for TSH and FT4 […]

Altered levels of the neurotransmitter dopamine are apparent in various conditions, such as Parkinson's disease and depression. In research published in ChemistrySelect, investigators describe a quick, sensitive, and simple test to determine dopamine levels in biological fluids. The method could help clinicians spot abnormal blood levels of dopamine in patients, thorazine d anik jean potentially allowing for earlier disease detection. […]

Individuals with chronic medical conditions may experience self-stigma, or negative beliefs, emotional reactions, and behaviors towards themselves as a result of their illness. New research published in the Journal of Diabetes Investigation found a link between self-stigma and glycated hemoglobin (HbA1c)-;a marker of blood glucose levels-;in adults with type 1 diabetes. The study included 109 adults in Japan with type […]

RNA viruses, such as the coronavirus that causes COVID-19, are in a life-and-death race the moment they infect a cell. These viruses have only minutes to establish their replication machinery inside the host cell before the genetic instructions contained in their vulnerable RNA genomes – which are more fragile than DNA – would otherwise be destroyed by cellular housekeeping. If […]

Inhibiting a particular protein in cancer-killing immune cells might improve the long-term effectiveness of CAR T-cell and other immune checkpoint therapies, according to a new study by researchers at The Ohio State University Comprehensive Cancer Center—Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC—James). Published in the journal Nature Immunology, the animal study examined the function of […]

A team of researchers at the University of Victoria, working with a colleague from York University, both in Canada, has found that going for a short walk outdoors provides people with more mental health benefits than going for a same-length walk inside. In their study, published in the journal Scientific Reports, the group asked volunteers to walk indoors or outdoors […]

The amount of time spent in moderate and vigorous physical activity every day is linked to mid-life brain power, indicates research published online in the Journal of Epidemiology & Community Health. This intensity level seems to be the best for working memory and mental processes, comparison of the combination of fenofibrate and simvastatin versus pravastatin such as planning and organization, […]