Scientific excellence requires diversity—research conducted by men and women, by people from different backgrounds and with varied worldviews. The need for diversity extends to scientific experiments themselves, but even today the vast majority of studies in the life sciences are done on male mice only, which could harm the findings, as well as our ability to extrapolate from them to […]

Plasma levels of three proteins involved in growth hormone activity showed significant links to the controllability of type 2 diabetes in adolescents, a finding that suggests these proteins may serve as risk markers for incident type 2 diabetes and help identify kids who could benefit from aggressive preventive care. Dr Chang Lu “Plasma growth hormone mediators are associated with glycemic […]

University of Texas at Dallas researchers have developed an artificial intelligence tool that could predict the risk of cardiac arrest in children hospitalized in cardiac intensive care units. The technology is the latest work from the Statistical Artificial Intelligence and Relational Learning Group, a UT Dallas research lab where experts develop AI to assist health care providers. The researchers aim […]

New drugs are being developed and used to combat a variety of malignancies. Among these is lenvatinib, an antagonist of multiple growth factors, including vascular endothelial growth factor receptor (VEGFR) 1-3, omeprazole teva rimafar 20mg fibroblast growth factor receptor (FGFR) 1-4, and platelet derived growth factor receptor alpha, which allows this agent to inhibit angiogenesis and cell proliferation. Lenvatinib is […]

Babies who were exposed to antenatal corticosteroids are at an increased risk of adverse health outcomes later on, according to new research published in the BMJ.  Antenatal corticosteroids are considered a key intervention for pregnant people who are at risk of preterm delivery earlier than 34 weeks. The drugs reduce the risk for perinatal and neonatal death, and decrease the […]

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SEATTLE, Washington — Treatment with pegcetacoplan (Syfovre, Apellis Pharmaceuticals) produced clinically meaningful reductions in the growth of geographic atrophy (GA) lesions through month 30, according to interim results presented at the annual meeting of the American Society of Retina Specialists. These reductions could delay GA progression into the central fovea and preserve vision in many patients with this form of […]

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by multisystem involvement. Systemic sclerosis (SSc) or scleroderma is another rheumatic autoimmune disease that affects blood vessels, skin, and visceral organs. EULAR has previously published recommendations for the management of these two conditions focused on pharmacological drugs,1,2 but different non-pharmacological interventions may also be suitable for these patients to manage […]

A new Annals “In the Clinic” provides a detailed summary of contraceptive methods and presents evidence-based discussion points that physicians can use to initiate a dialog with their patients of reproductive potential. The timing of this release is crucial as pregnancy-associated mortality is on the rise, abortion access is decreasing, and the mini pill has just been approved for over-the-counter […]

Rare diseases… not so rare IRCM expertise in rare diseases Source: Read Full Article