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Research carried out at Oxford’s Nuffield Department of Clinical Neurosciences has led to the development of a new blood-based test to identify the pathology that triggers Parkinson’s disease before the main symptoms occur. This could allow clinicians to screen for those individuals at high risk of developing the disease and facilitate the timely introduction of precision therapies that are currently […]

Overall statin use for primary prevention increased since 1999 to 2000 but has plateaued since 2013 to 2014, according to a research letter published online Dec. 5 in the Annals of Internal Medicine. Casey J. Kim, M.D., from the Beth Israel Deaconess Medical Center in Boston, and colleagues describe trends in statin use for primary prevention across indication categories and […]

By fusing the power of artificial intelligence with new molecular techniques that also seem ripped from science fiction, researchers at UCSF have mapped the microscopic world of autism spectrum disorder in unprecedented detail, pointing toward possible therapies for a subset of patients who have specific genetic mutations, according to a new study. “This opens up kind of a Goldilocks of […]

Many emerging and re-emerging infectious diseases, especially zoonotic diseases such as Ebola or new coronaviruses, emerge as the result of intensified human activities such as deforestation, expansion of agricultural land, and increased hunting and trading of wildlife. In a new study, published in the journal Lancet Planetary Health, researchers identified public and private companies operating in economic sectors associated with […]

A new research paper was published in Oncotarget is titled, “Osteopontin induces mitochondrial biogenesis in deadherent cancer cells.” Metastasizing cells display a unique metabolism, which is very different from the Warburg effect that arises in primary tumors. Over short time frames, oxidative phosphorylation and ATP generation are prominent. Over longer time frames, mitochondrial biogenesis becomes a pronounced feature and aids […]

Reviewed University of Queensland-led research shows being overweight can impair the body's antibody response to SARS-CoV-2 infection but not to the protection offered by vaccination. Research lead, School of Chemistry and Molecular Biosciences PhD candidate Marcus Tong, said the finding built on the team's existing research on how COVID-19 affects people who are overweight. We've previously shown that being overweight […]

In a consensus statement issued by the International Consensus Conference on Concussion in Sport and published online Dec. 4 in Pediatrics, recommendations are presented for managing sport-related concussion among children and adolescents. Gavin A. Davis, M.B.B.S., from the Murdoch Children’s Research Institute in Melbourne, Australia, and colleagues developed recommendations regarding SRC in children and adolescents (age 5 to 12 and […]

A study suggests that the response of immune system cells inside the protective covering surrounding the brain may contribute to the cognitive decline that can occur in a person with chronic high blood pressure. This finding, published in Nature Neuroscience, may shed light on new ways to counteract the effects of high blood pressure on cognition. “The role of immune […]