Does Mixing an SSRI With an Anti-amyloid Up Bleeding in AD?

Clinicians from Switzerland are urging caution when prescribing an anti-amyloid medication in a patient with Alzheimer’s disease (AD) also taking a selective serotonin reuptake inhibitor (SSRI) antidepressant. SSRIs decrease serotonin and cause hemostatic interference such as decreased platelet aggregability and activity with prolongation of bleeding time, they point out in a letter published online August 16 in Alzheimer’s & Dementia. […]

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Recently published in the journal American Journal of Physiology, a Brazilian study demonstrated for the first time that survivors of severe COVID-19 infections may have elevated muscle sympathetic nerve activity (MSNA) in response to mental stress. The study was carried out by the D’Or Institute for Research and Education (IDOR), in partnership with the University of São Paulo (USP), the […]

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Age-related changes in the blood system can exacerbate colon cancer

Reviewers’ Notes Researchers at the University of Florida College of Medicine have discovered how common age-related changes in the blood system can make certain colon cancers grow faster. The study, to be published August 24 in the Journal of Experimental Medicine (JEM), also suggests how these effects might be therapeutically targeted to reduce tumor growth and improve patient survival. As […]

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Reviewers’ Notes Researchers have developed an engineered adeno-associated virus (AAV) vector that yields high transduction of brain vascular pericytes and smooth muscle cells. The study describing the characterization of this novel AAV capsid is published in the peer-reviewed journal Human Gene Therapy. In the current study, Servio Ramirez, from Temple University School of Medicine, lopid vs tricor which is better […]

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Metabolite in urine predicts diabetic kidney failure 5–10 years early: Oral therapeutic drug shows promise in mice

Urine levels of adenine, a metabolite produced in the kidney, are predictive and a causative biomarker of looming progressive kidney failure in patients with diabetes, a finding that could lead to earlier diagnosis and intervention, researchers from The University of Texas Health Science Center at San Antonio (also called UT Health San Antonio) reported in the Journal of Clinical Investigation. […]

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<img class="aligncenter" src="https://scx1.b-cdn.net/csz/news/800a/2023/scientists-create-a-to.jpg" alt="Scientists create a tool to identify individuals at risk of developing different myeloid leukemias" title="Summary of driver mutations in the 11 most commonly mutated genes in CH. a, Percentages of cases per driver gene among the 22,735 UKB participants with CH. b, Distribution of clone sizes (VAF) by driver mutation. Medians are depicted by black dots and […]

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Reviewers’ Notes In the rural United States, an adolescent who drinks heavily has a 43% greater probability of carrying a handgun in the following year, according to a study published this month in The Journal of Rural Health. While there has been a lot of research on this correlation in urban areas, little is known about the association between alcohol […]

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