The quest to conquer latent HIV and end the AIDS pandemic

HIV latency and the trouble with finding a cure The SĂŁo Paulo Patient’s Treatment The control group persisted on their normal ART regimen. Another group received their normal ART regimen with 2 additional drugs, dolutegravir and miravoc, the latter of which has been shown to act as a latency reversal agent (LRA). In the third group, Diaz gave enhanced ART […]

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Withholding Intubation Benefits Comatose Poisoning Patients

TOPLINE: In comatose patients with a suspicion of acute poisoning, opting for a conservative approach by refraining from intubation has a significant clinical advantage concerning the combined outcomes of in-hospital mortality, duration of intensive care unit (ICU) stay, and length of hospital stay. METHODOLOGY: This multicenter randomized trial conducted in 20 emergency departments (EDs) and 1 ICU in France included […]

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The CDC has issued an update on a salmonella outbreak linked to cantaloupes, raising the number of states to 34 after Alaska and Kansas were found to have cases. The number of people who have been sickened has increased, but the death toll remains at two. The U.S. Food and Drug Administration and the Centers for Disease Control and Prevention […]

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Study shows how aging affects communication between skin cells

Reviewed A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 22, entitled, "Chronological aging impacts abundance, function and microRNA content of extracellular vesicles produced by human epidermal keratinocytes." The disturbance of intercellular communication is one of the hallmarks of aging. In their […]

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Reviewed A simple-to-apply, needle-free vaccine patch is being developed to protect people from the potentially deadly mosquito-borne Zika virus. A prototype using The University of Queensland-developed and Vaxxas-commercialised high-density microarray patch (HD-MAP) has delivered a University of Adelaide-developed vaccine and elicited an effective immune response to Zika virus in mice. UQ alum and Vaxxas researcher Dr Danushka Wijesundara said Zika […]

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Harnessing the power of a parasite that can stop pain

For the first time, scientists have begun to figure out why the disfiguring skin lesions caused by cutaneous leishmaniasis don’t hurt. Researchers analyzed leishmaniasis lesions on mouse skin to detect metabolic signaling pathways that differed from uninfected mice. Results suggested the parasites that cause the disease change pain perception—presumably as a way to delay treatment and promote their own survival. […]

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Scientists use AI-generated images to map visual functions in the brain

Researchers at Weill Cornell Medicine, Cornell Tech and Cornell’s Ithaca campus have demonstrated the use of AI-selected natural images and AI-generated synthetic images as neuroscientific tools for probing the visual processing areas of the brain. The goal is to apply a data-driven approach to understand how vision is organized while potentially removing biases that may arise when looking at responses […]

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Skin-to-skin contact between parent and infant during the first hours after a very premature birth helps develop the child’s social skills. This is according to a new study published in JAMA Network Open by researchers from Karolinska Institutet and others. The study also shows that fathers may play a more important role than previous research has shown. In current practice, […]

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