Migraine is underdiagnosed and undertreated

Migraine is a common chronic health condition and a leading cause of disability globally. However, even in Canada, with a universal health-care system, migraine is underdiagnosed and undertreated. This is an important public health issue since migraine is associated with reduced quality of life, affecting social life and relationships, productivity and overall health. Increasing awareness of migraine symptoms is critical […]

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Opioid addiction starts at the ER, according to studies

Legitimate prescriptions of opioids as painkillers are a contributing factor in long-term addiction to these substances. This is what Sarah Eichmeyer of Bocconi’s Department of Economics and Jonathan Zhang of McMaster University in Canada found and described in two recent papers, “Pathways into Opioid Dependence: Evidence from Practice Variation in Emergency Departments,” published on the American Economic Journal, and “Primary […]

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CHLA expert offers update on the latest COVID-19 vaccine information and precautions

Reviewers’ Notes The coronavirus pandemic is no longer a national emergency, but the virus that causes COVID-19 isn't gone-;and neither is the risk of getting the disease. For parents, navigating when to get their child vaccinated and knowing how to best protect their child from COVID-19 can be complicated. We spoke to Michael Smit, MD, MSPH, Hospital Epidemiologist and Medical […]

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High cholesterol: Nutritionist reveals top prevention tips Cholesterol is not all bad. A small amount of the waxy substances helps to build the structure of cell membranes and make hormones. However, high levels of “bad” cholesterol can spell bad news for your arteries, hiking your risk of heart disease and stroke. Diet represents a double-edged sword in this process. While […]

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Intranasally administered SARS-CoV-2 RBD-based nanoparticle vaccine provides protection against lung pathology and viral load

In a recent study published in Scientific Reports, researchers working at Ohio State University in the United States of America (USA) developed an intranasal subunit vaccine. Study: An intranasal vaccine comprising SARS-CoV-2 spike receptor-binding domain protein entrapped in mannose-conjugated chitosan nanoparticle provides protection in hamsters. Image Credit: Skylines/Shutterstock.com Named the NARUVAX-C19/Nano, the vaccine is based on the receptor-binding domain (RBD) of severe […]

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Adult cancer diagnoses reduced by half in April 2020 during the COVID-19 pandemic in the U.S

Reviewers’ Notes A new study from researchers at the American Cancer Society (ACS) found monthly adult cancer diagnoses decreased by half in April 2020 during the COVID-19 pandemic in the United States. The largest decrease was for stage I cancers, resulting in a higher proportion of late-stage diagnoses. The study is the most comprehensive research to date about the effects […]

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Reviewers’ Notes Non-invasive brain stimulation, combined with cognitive training, could significantly improve symptoms of attention deficit hyperactivity disorder (ADHD) in children, according to new research jointly led by the University of Surrey and the Hebrew University of Jerusalem. In a clinical trial involving 23 unmedicated children (6 to 12 years old) with ADHD, researchers set out to find out whether […]

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Sex differences in depression: Including transgender and intersex populations in mental health research

Reviewers’ Notes In 2016, recognizing that lack of research in female animals was hampering the success of treatments for mood disorders, the National Institutes of Health (NIH) changed its policy for basic research to include sex as a biological variable for basic research, a move that triggered an explosion of research into sex differences. "Building a strong unbiased foundation of […]

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An interim safety analysis of the first randomized controlled trial of its kind involving over 80,000 Swedish women published in The Lancet Oncology journal, finds artificial intelligence (AI)-supported mammography analysis is as good as two breast radiologists working together to detect breast cancer, without increasing false positives and almost halving the screen-reading workload. However, the final trial results looking at […]

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