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National University of Singapore researchers developed an approach to target highly resistant triple-negative breast cancers (TNBCs) by interfering with their energy production using cytotoxic gold-metformin prodrugs. Metformin is a widely prescribed “over-the-counter” medication for Type 2 diabetes. There is some evidence that patients taking metformin for a long time have significantly reduced risk of developing cancer. However, despite well-characterized anticancer […]

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Miniaturized models of neuron-muscle interactions give insight in ALS

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Skeletal muscles enable voluntary movements and are controlled by a special type of neurons called motor neurons, which make direct contact with skeletal muscles through so-called neuromuscular junctions (NMJs). It is through NMJs that skeletal muscles receive signals making them contract or relax. In certain neurodegenerative diseases, such as amyotrophic lateral sclerosis (ALS), NMJs are destroyed, leading to progressive muscle […]

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Ongoing testing of immunized individuals will be key to mitigate future COVID-19 outbreaks

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In rare cases, people who have been fully vaccinated against COVID and are immune to the virus can nevertheless develop the disease. New findings from The Rockefeller University now suggest that these so-called breakthrough cases may be driven by rapid evolution of the virus, and that ongoing testing of immunized individuals will be important to help mitigate future outbreaks. The […]

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China reports 19 new COVID-19 cases vs 6 a day earlier

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FILE PHOTO: People line up at a coronavirus disease (COVID-19) mobile vaccination unit in Beijing, China, April 14, 2021. REUTERS/Thomas PeterSHANGHAI (Reuters) – China reported 19 new COVID-19 cases on April 22, up from six cases a day earlier, the national health authority said on Friday. The National Health Commission said in a statement all of the new cases were […]

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How studying biases about veterans could help improve their post-military careers

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Common stereotypes about veterans and their skills might limit their chances to excel once they leave the military and join the civilian workforce. Social psychologist Aaron Kay, a management professor at Duke University’s Fuqua School of Business, suggests that if scholars approach research about military veterans the same way they study biases related to gender, class and race, those insights […]

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When President Joe Biden announced his intention to launch a national website to facilitate COVID-19 vaccinations by May 1, many in the health IT industry had flashbacks.   Some probably had recent memories of the Trump administration’s haphazard coronavirus response – not least its move to a new data reporting system, where to buy cheap citalopram online pharmacy without prescription […]

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Followers of the zodiac may want to mark their calendars for the full moon in Scorpio on April 26. The moon is also known as a Pink Moon (via Bustle). Full moons are known to highlight certain situations in our lives. However, the sign of Scorpio is veiled in privacy, which means that you may feel like keeping your emotions […]

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Study finds stereotactic body radiotherapy is safe for treating multiple metastases

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A phase 1 clinical trial led by investigators at the University of Chicago Medicine testing the effects of stereotactic body radiotherapy for treating multiple metastases has determined that treatments used for single tumors can also be safely used for treating patients with multiple metastases. The study was run through NRG Oncology and sponsored by the National Cancer Institute. The results […]

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