US Cancer Drug Approvals Ensure Access but Not Value

Cancer drugs that have been approved in the United States are often not immediately approved in the United Kingdom and Canada, owing to uncertainty over benefits and harms as well as extremely high prices, two new studies in JAMA Internal Medicine indicate. The oncology drug approval process of the US Food and Drug Administration (FDA) is “broken,” concludes an accompanying […]

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The Ethics of Animal Models in Preclinical Testing

Preclinical testing is vital for assessing the safety profiles and potential efficacy of new therapeutics in development. Animal testing is one of two routes usually selected for the preclinical stage, the other being testing on human cell cultures in vitro. While scientists must provide a sound rationale for choosing the animal model over the in vitro methodology to ensure that […]

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Covid vaccine side effects: Chills more likely if previously infected with coronavirus

Covid-19: Lord Bilimoria says he’s ‘optimistic’ for roadmap When you subscribe we will use the information you provide to send you these newsletters.Sometimes they’ll include recommendations for other related newsletters or services we offer.Our Privacy Notice explains more about how we use your data, and your rights.You can unsubscribe at any time. Individuals have unwittingly helped to spread the coronavirus […]

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Although guidelines do not recommend use of opioids to manage pain for individuals with knee osteoarthritis, a recent study published early online in Arthritis Care & Research, an official journal of the American College of Rheumatology and the Association of Rheumatology Professionals, buy erythromycin canadian pharmacy no prescription estimates that 858,000 Americans use opioids such as tramadol and oxycodone for […]

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New biomarker could help identify people at risk of Alzheimer's disease

Early diagnosis of Alzheimer's disease has been shown to reduce cost and improve patient outcomes, but current diagnostic approaches can be invasive and costly. A recent study, published in the Journal of Alzheimer's Disease, has found a novel way to identify a high potential for developing Alzheimer's disease before symptoms occur. Ray Romano, Ph.D., RN, completed the research as part […]

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New hydrogel-based materials that can change shape in response to psychological stimuli, such as water, could be the next generation of materials used to bioengineer tissues and organs, according to a team of researchers at the University of Illinois Chicago. In a new paper published in the journal Advanced Functional Materials, the research team -; led by Eben Alsberg, the […]

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Researchers use machine learning to identify autism blood biomarkers

Using machine learning tools to analyze hundreds of proteins, UT Southwestern researchers have identified a group of biomarkers in blood that could lead to an earlier diagnosis of children with autism spectrum disorder (ASD) and, in turn, more effective therapies sooner. The identification of nine serum proteins that strongly predict ASD were reported in a study published today by PLOS […]

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Fauci Introduces New Acronym for Long COVID

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. As officials scramble to get vaccines and protective gear to the public, scientists are working overtime to gain knowledge of the long-term effects of COVID-19, said Anthony Fauci, MD, during a wide-ranging briefing at the White House today. “Many of you are now aware of what […]

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Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Novavax says it plans to apply for US Food and Drug Administration (FDA) emergency use authorization for its COVID-19 vaccine in the second quarter of the year. Gregory M. Glenn, MD, president of research and development at the Gaithersburg, Maryland-based company, said on a Washington Post […]

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