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Quiescence is a temporary cell cycle state where populations of cells rest and do not replicate, before they are activated and re-enter the cell cycle. Credit: jovan vitanovski/Shutterstock.com Entering and exiting the cell cycle The cell cycle is highly organised and divided into four phases (G1, S, G2 and M). Checkpoints are used to ensure that the important events of […]

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NOTICE: This Consumer Medicine Information (CMI) is intended for persons living in Australia. AJOVY® CONSUMER MEDICINE INFORMATION VER 1.0 This medicine is subject to additional monitoring. This will allow quick identificationof new safety information. You can help by reporting any side effects you may get.You can report side effects to your doctor, or directly at www.tga.gov.au/reporting-problems . Fremanezumab (Fre-ma-nay-zoo-mab) Consumer Medicine […]

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Visceral larva migrans is a zoonotic infestation by certain nematode parasites which are found in dogs and cats. These are roundworm larvae of the species Toxocara canis (T. canis) and (less frequently) Toxocara cati (T. cati). Toxocara canis second stage larvae hatch from eggs. Mechanism of infection When roundworms infest these animals, they live and lay eggs in the intestines. […]

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What are PARP inhibitors?

Poly ADP-ribose polymerase (PARP) inhibitors are pharmaceutical drugs that can be used to treat many different forms of cancer, including ovarian and breast cancer. They manipulate DNA repair pathways, causing the death of cancerous cells. Image Credit: Molekuul_be / Shutterstock PARP mechanism of action In mammals, 17 PARP family members have been discovered, and only 6 of these synthesize poly […]

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NOTICE: This Consumer Medicine Information (CMI) is intended for persons living in Australia. DYNASTAT® (die-na-stat) parecoxib Consumer Medicine Information What is in this leaflet This leaflet answers some common questions about Dynastat powder for injection. It does not contain all the available information. It does not take the place of talking to your doctor or nurse. All medicines have risks […]

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NOTICE: This Consumer Medicine Information (CMI) is intended for persons living in Australia. ZETLAM lamivudine CONSUMER MEDICINE INFORMATION What is in this leaflet Please read this leaflet carefully before you take ZETLAM tablets. This leaflet answers some common questions about ZETLAM. It does not contain all the available information. It does not take the place of talking to your doctor […]

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Phylogeny is the representation of the evolutionary history and relationships between groups of organisms. The results are represented in a phylogenetic tree that provides a visual output of relationships based on shared or divergent physical and genetic characteristics. Phylogenetic analysis is dependent on the type of data inputted, the number of species and the range of evolutionary relationships interpreted. Detailed […]

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NOTICE: This Consumer Medicine Information (CMI) is intended for persons living in Australia. DIFICID® fidaxomicin tablets Consumer Medicine Information (CMI) What is in this leaflet This leaflet answers some common questions about fidaxomicin tablets. It does not contain all the available information.It does not take the place of talking to your doctor or pharmacist. All medicines have risks and benefits.Your […]

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NOTICE: This Consumer Medicine Information (CMI) is intended for persons living in Australia. DESFAX Desvenlafaxine Consumer Medicine Information What is in this leaflet This leaflet answers some common questions about Desfax. It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist or asking questions. All medicines have risks and […]

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Total Internal Reflection Fluorescence (TIRF) Microscopy Applications

Total internal reflection fluorescence (usually abbreviated as TIRF) microscopy is an imaging method that illuminates fluorescence in a shallow area of the specimen in order to enhance the signal-to-noise ratio. This technique is widely applied in imaging small structures or molecules. Caleb Foster | Shutterstock Methodology of TIRF microscopy In TIRF microscopy, fluorescent molecules are in a sample in an […]

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