Holliday Junctions in DNA Replication

A holliday junction is a branched nucleic acid structure composed of four double-stranded arms joined together. kornilov007 | Shutterstock Holliday junctions can be formed during genetic recombination and affect many biological processes, including DNA replication and gene regulation. DNA replication In mitosis, DNA replication is initiated through the actions of various multiprotein complexes that recognize the start sites within a […]

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NOTICE: This Consumer Medicine Information (CMI) is intended for persons living in Australia. APO-PROCHLORPERAZINE TABLETS Contains the active ingredient, prochlorperazine (as maleate) Consumer Medicine Information What is in this leaflet This leaflet answers some common questions about this medicine. It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist. […]

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NOTICE: This Consumer Medicine Information (CMI) is intended for persons living in Australia. SALAZOPYRIN® Tablets and EN tablets Sulfasalazine Consumer Medicine Information What is in this leaflet “Salazopyrin” will be used in this leaflet to refer to the “plain” and “EN” tablets unless specified. This leaflet answers some common questions about Salazopyrin. It does not contain all the available information […]

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Biosimilar Drugs: Overview and Industry Challenges

Biosimilar drugs (also known as biosimilars, or follow-on biologics) are almost identical versions of a medical product or a drug that are produced by a different company to the parent company. They are typically produced after the original patent for a product expires and must be approved by a regulatory body before entering the market. This article will cover: What […]

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NOTICE: This Consumer Medicine Information (CMI) is intended for persons living in Australia. REAPTAN® 5/5; 5/10; 10/5; 10/10 Perindopril/amlodipine [pronounced per-in-do-pril/ am-load-i-peen] Consumer Medicine Information WHAT IS IN THIS LEAFLET This leaflet answers some common questions about REAPTAN. It does not contain all the available information about this medicine. Reading this leaflet does not take the place of talking to […]

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NOTICE: This Consumer Medicine Information (CMI) is intended for persons living in Australia. TERRY WHITE CHEMISTS IRBESARTAN HCTZ Irbesartan and hydrochlorothiazide Consumer Medicine Information What is in this leaflet This leaflet answers some common questions about irbesartan HCTZ. It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist. All […]

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Transmission Raman Spectroscopy Advantages and Limitations

Transmission Raman Spectroscopy is a variation of transmission Raman spectroscopy that is often used to probe the bulk properties of samples that scatter diffusely. It is particularly useful for the analysis of materials that are opaque or turbid. Skip to: Understanding Transmission Raman Spectroscopy Transmission Raman Spectroscopy versus conventional Raman spectroscopy Advantages of Transmission Raman Spectroscopy Transmission Raman Spectroscopy in […]

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Whole genome bisulfite sequencing, or WGBS, is a next-generation sequencing technique to analyze DNA methylation. Image Credit: Egorov Artem / Shutterstock DNA methylation is an epigenetic mechanism to regulate gene expression and involves adding a methyl group to a cytosine base. Abnormal methylation patterns have been associated with several conditions and diseases, such as cancer. Since the development of WGBS, […]

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Glutamate receptors are the primary mediators of excitatory transmission in the central nervous system and are mostly located on the dendrites of postsynaptic neuronal and glial cells, such as astrocytes and oligodendrocytes. Image Credit: Juan Gaertner/Shutterstock.com They bind to the neurotransmitter and amino acid glutamate, and their activity is linked with numerous other neurotransmitter pathways. Glutamate receptors are essential in […]

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Bioorthogonal Chemistry in Research

A bioorthogonal reaction is a reaction within a living system that does not interfere or interact in any way with native biochemistry of the system. The phrase ‘bioorthogonal’ was coined in 2003, and bioorthogonal chemistry is now widely used to study biomolecules in living systems. Pavel Chukhov | Shutterstock The functional groups participating in the reaction are inert to biologically […]

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