The US Food and Drug Administration’s (FDA’s) review of the biologics license application (BLA) for bimekizumab for the treatment of psoriasis is continuing. A decision on the approval application has been delayed until the third quarter of this year, according to a June 26 announcement by the manufacturer, UCB. The FDA’s decision had been expected by the end of June. […]
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The threat of further strikes by British nurses ended on Tuesday, after the Royal College of Nursing said a ballot on industrial action had failed to meet the legal threshold. The RCN said more than 100,000 members voted in favor of more strikes but turnout was only 43 percent—below the statutory minimum of 50 percent. Nurses in England were voting […]
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While the human mind develops during aging, the mechanism of development remains unknown but may be the result of brain alteration derived from life style and environment. Schizophrenia usually develops during puberty through early adulthood and is suspected to interrupt brain development, but the degree of neural alteration remains unclear in schizophrenia. A new study, published in PLOS ONE, performed […]
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A multidisciplinary team from the University of Geneva (UNIGE) and the Geneva University Hospitals (HUG) has for the first-time used bacteriophages to successfully treat a patient suffering from an antibiotic-resistant chronic bacterial lung infection. This success was achieved thanks to a highly personalized, multidisciplinary approach involving the selection of a bacteriophage specific to the patient’s multidrug resistant bacteria. While phages […]
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TOPLINE: CD19-targeting CAR T cells may effectively treat refractory antisynthetase syndrome, according to a case study. METHODOLOGY: Previous case studies found that CD19-targeting chimeric antigen receptor (CAR) T cells were efficacious in treating autoimmune conditions such as refractory systemic lupus erythematosus. CD19-targeting CAR T cells were administered to a 41-year-old male patient with antisynthetase syndrome with progressive myositis and interstitial […]
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Bethany Birch had pain in her diaphragm on and off for eight months in 2016. She knew it was triggered by food, so she said she tried taking an antacid. That helped a little, but, eventually, she avoided eating altogether. She estimated she lost 25 pounds in that time. One night that September, the pain would not go away for […]
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In a recent article published in the Science Immunology Journal, researchers probed for antibody binding against all seven human coronaviruses (hCoVs) and 49 animal coronaviruses (aCoVs) represented as 12,924 peptides within a phage immunoprecipitation sequencing (PhIP) library. The study used viruses harboring in multiple hosts, including bats, rodents, birds, raccoons, pangolins, etc., with the potential to spill over to humans. […]
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Along with all global sectors, the dairy industry is working to reduce its environmental impact as we look toward a shared 2050 net zero future. Research is currently focused on greenhouse gas mitigation strategies that do not compromise animal health and production, but many discussions maintain that a radical transformation—involving reducing animal-based foods and increasing plant-based foods—is needed in our […]
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The role of mediation in preventing disputes between parents and doctors about a seriously ill child’s medical treatment from escalating to litigation may be more limited than hoped for, suggests an analysis of rulings, published online in the Archives of Disease in Childhood. Mediation might have avoided only just under half of these published court cases heard since 1990 in […]
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