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Longer cumulative use of medication to treat attention-deficit/hyperactivity disorder (ADHD) is associated with a small, but statistically significant, increased risk for cardiovascular disease (CVD), results of a large Swedish nested case-control study suggest. The increased risk was evident only for hypertension and arterial disease, was dose-dependent, and was higher for stimulant than nonstimulant ADHD medications. “Clinicians should be vigilant in […]

In Alzheimer’s disease and related dementias, cognitive decline is driven by the over-accumulation of a normal brain protein known as tau. Wherever tau builds up, nearby brain tissue starts to degenerate and die. Now, researchers at Washington University School of Medicine in St. Louis have found—in mice—that Alzheimer’s-like tau deposits in the brain lead to the accumulation of a form […]

Medical oncologist W. Kimryn Rathmell, MD, PhD, will soon take the helm of the National Cancer Institute (NCI) as its new director. Late last week, US President Joe Biden announced the appointment of Rathmell, a renal cancer expert and chair of medicine at Vanderbilt University Medical Center, Nashville, to replace former NCI head Monica Bertagnolli, MD, after her recent Senate […]

Dr Dawn Harper on signs of vitamin B12 and vitamin D deficiency Vitamin B12 deficiency can lead to a variety of symptoms, some of which could be overlooked. The condition occurs when a lack of the vitamin, or folate, causes the body to produce abnormally large red blood cells that cannot function properly. The most common cause of vitamin B12 […]

Reviewed To age or not to age! How does aging affect organisms on a cellular level? What mechanisms help cells survive self-inflicted or external harm? It is known that lysosomes-;critically important cellular structures-;are crucial for digesting damaged cellular components and pathogens, and maintain stability within cells and tissues. But can they also be repaired, and if so, how? In a […]