Weight loss leads to an increase in skeletal muscle mitochondrial energy production efficiency

Weight regains is a common problem for weight loss individuals. A number of studies have shown that weight loss in overweight people results in a reduction in whole-body energy expenditure. This reduction in energy expenditure is disproportionate across tissues, known as energetic mismatch which primarily originates from lean tissue, thus increasing weight regain risk. Although this phenomenon has long been […]

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Experts say its not yet time to take off masks in the health care setting

A new commentary from infectious disease experts at George Washington University School of Medicine and the National Institutes of Health (NIH) says for patient safety, masking should continue in health care settings. This message conflicts with a recent commentary from authors from eight U.S. institutions suggesting that the time for universal masking is over. The commentary is published in Annals […]

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Fresh insights into the spread of damaging proteins that build up in the brains of people with Alzheimer’s disease could hold the key to stopping the condition from progressing, a study says. Researchers have discovered that synapses, spironolactone 25 mg used for which send essential signals through the brain, are also transporting toxic proteins known as tau around the brain. […]

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Wide-ranging strategies needed to eliminate racial and ethnic inequities in stroke care, say researchers

“Upstream” causes of health inequities related to stroke, such as structural racism and structural conditions of the places where people live, learn, work and play, have not been studied well, according to a new American Heart Association scientific statement. The statement, published today in Stroke, reviews the most recent research on racial and ethnic inequities in stroke care and outcomes; […]

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Specific TJA subgroups gain greater benefit from peripheral nerve blocks

Specific subgroups of patients undergoing total joint arthroplasty (TJA) experience greater benefit from peripheral nerve blocks (PNBs) in terms of reduction in complications, according to a study presented at the Annual Regional Anesthesiology and Acute Pain Medicine Meeting 2023, held from April 20 to 22 in Hollywood, Florida. Haoyan Zhong, from the Hospital for Special Surgery in New York City, […]

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First-in-human clinical trial tests experimental oral drug for removing radioactive contaminants

A first-in-human clinical trial of an experimental oral drug for removing radioactive contaminants from inside the body has begun. The trial is testing the safety, tolerability and processing in the body of escalating doses of the investigational drug product HOPO 14-1 in healthy adults. The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, […]

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Study illustrates unique genetic landscape in Newfoundland and Labrador with links to Ireland and England

A new study by RCSI University of Medicine and Health Sciences, based in Dublin, Ireland, and Sequence Bio, a genomics and precision medicine company based in St. John’s, Newfoundland and Labrador (NL), Canada, has produced the most detailed genetic analysis of people living in the Canadian province to date, demonstrating a unique founder population structure that could be used for […]

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Hagop Kantarjian, MD, has been named the recipient of the 2023 David A. Karnofsky Memorial Award by the American Society of Clinical Oncology (ASCO) in recognition of his practice-changing clinical-translational research in leukemia. This award is the society’s “highest scientific honor, and I am extremely happy and honored to receive it, cymbalta average dosage ” Kantarjian commented in an interview […]

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Experts provide a new clinical picture of sarcopenic obesity

Proteins and weight training could help if obese patients are suffering from muscle atrophy. However, the problem is usually not recognized, according to Prof. Dr. Bischoff from the University of Hohenheim. It is a condition that has received little attention to date, and it mainly affects people who are obese: due to a lack of exercise, this population group can […]

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