Study finds COVID-19 vaccine effectiveness against Omicron rapidly wanes over time

In a recent study published in the JAMA Network Open, researchers performed a systematic review and meta-analysis using secondary data from 40 published studies reporting time-varying, population-level coronavirus disease 2019 (COVID-19) vaccine effectiveness (VE) estimates against laboratory-confirmed infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants, Omicron or Delta, and symptomatic disease. The primary outcome for this secondary data […]

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lorazepam dosage 4 mg

A collaboration between UC San Diego Health and 211 San Diego, a region-wide, non-profit referral service that connects anyone living in San Diego County to community, health, social and disaster services, famotidine actions and uses will help to improve patient outcomes by addressing social determinants. The region's only academic medical center is the first hospital system in the county to […]

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Epilepsy medicine during pregnancy associated with increased risk of psychiatric disorders in children

Some types of epilepsy medicine taken during pregnancy are associated with an increased risk of severe psychiatric disorders in children. This is the conclusion of a comprehensive study of 38,000 children of mothers with epilepsy by researchers from Aarhus University. The research is published in the journal JAMA Neurology. While it has long been known that some forms of epilepsy […]

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Study validates organoids as tool for studying fetal intestine development

Developmental biologists have learned a great deal about how the human digestive tract functions through many years of studies involving fish, frogs, and rodents along with detailed explorations of individual human cells. But nothing quite matches the learning that could be achieved from studying actual human organ systems as they form. Yet for obvious reasons, running experiments on growing human […]

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Escorting a key immune protein to its demise to control inflammation

Monash University researchers have discovered a key mechanism in the body’s immune system that helps control the inflammatory response to infection. The discovery could help pave the way for more targeted therapies in a range of inflammatory conditions, such as autoimmunity and neuroinflammatory disease. The innate immune system is the body’s first line of defense against pathogens. Innate immune proteins […]

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Study finds its cost-effective to diagnose intellectual disabilities with whole genome sequencing

Researchers at Karolinska Institutet and Karolinska University Hospital have together with health economists at Linköping University analyzed costs for various methods to diagnose genetic causes of intellectual disability. The study, published in Scientific Reports, shows that the costs when using whole genome sequencing as a first-line diagnostic test were lower compared to chromosomal microarray analysis. An examination of the entire […]

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Determining a global standard for screening and diagnosing gestational diabetes

In light of several new trials challenging the status quo, the British Medical Journal (BMJ) approached Dr. Sara White to address the challenging question of how best to screen and diagnose gestational diabetes. Gestational diabetes, commonly referred to as GDM, is high blood sugar (glucose) which occurs for the first time during pregnancy and commonly disappears after giving birth. The […]

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Study pinpoints how gut microbes boost the body's response to cancer immunotherapy

Cancer immunotherapy has transformed the treatment of many types of cancer. Yet, for reasons that remain poorly understood, not all patients get the same benefit from these powerful therapies. One potent factor in treatment outcome appears to be an individual's gut microbiota -; the trillions of microorganisms that live in the human intestine -; according to new research led by […]

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Long-term PM2.5 exposure associated with increase in hospital procedures in heart failure patients

Long-term exposure to fine particulate matter air pollution was associated with an increase in hospital procedures in heart failure patients, according to a study published May 3, 2023, in the open-access journal PLOS ONE by Samantha Catalano from the University of North Carolina at Chapel Hill, USA, and colleagues. Tiny airborne particles smaller than 2.5μm in diameter (PM2.5) are air […]

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