MADRID — Should patients with resectable non–small cell lung cancer (NSCLC) receive adjuvant therapy, neoadjuvant therapy, or both experts asked during a special session at the European Society for Medical Oncology (ESMO) Congress 2023 on October 21. Though immunotherapy is beneficial in resectable NSCLC, “we actually don’t know how much of the effect [is due to] the adjuvant and how […]
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An international clinical trial led by physician Jeffrey L. Carson, distinguished professor of medicine at Rutgers Robert Wood Johnson Medical School, found that a liberal blood transfusion given to patients who have had a heart attack and have anemia may reduce the risk of a reoccurrence and improve survival rates. The results of the trial, Myocardium Infarction and Transfusion (MINT), […]
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A new editorial paper was published in Oncotarget, titled “GBP3-STING interaction in glioblastoma coordinates autophagy, anti-oxidative, and DNA repair programs in response to temozolomide.” In their recent editorial, researchers Jun Ma, Ziyu Wang, Clark C. Chen, and Ming Li from the University of Minnesota discussed the methylating agent, Temozolomide (TMZ). TMZ is the standard adjuvant chemotherapeutic drug for glioblastoma, which […]
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Snoring: Doctor explains how to sleep better at night Almost half of Britons are guilty when it comes to snoring at night. While it is typically beyond our control, it can be extremely frustrating for anyone you’re sharing a bed with. While it can be a sign of something more serious, like sleep apnoea, it can also be linked to […]
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Fake injection pens of Ozempic, a hugely popular diabetes drug that went viral on social media as a way to lose weight, are circulating in Europe, drug authorities have warned. Ozempic, which involves a once-weekly injection from a pre-filled pen, was originally developed to treat type 2 diabetes. However since it became clear the drug was effective for weight loss, […]
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Several epidemiological studies have suggested a link between being born too small and abnormal neurodevelopment in childhood and later life. However, there is little evidence that these factors are causally related to a hostile intrauterine environment. A new study in JAMA Psychiatry discusses this topic in greater depth. Study: Intrauterine growth and offspring neurodevelopmental traits: a Mendelian Randomization analysis of the […]
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A research collaboration led by the University of Chinese Academy of Sciences, China, investigated the role of CHIT1, a protein associated with microglia, in aging. In a paper, “CHIT1-positive microglia drive motor neuron aging in the primate spinal cord,” published in Nature, the group identifies distinct states of microglia in the aged spinal cord associated with aging-related changes. It links […]
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Type 1 diabetes is an autoimmune disease that causes the body’s immune system to attack and destroy insulin-producing beta cells in the pancreas. Traditional management of type 1 diabetes has primarily involved replacing the missing insulin with injections which, though effective, can be expensive and burdensome. A new study, published in Cell Reports Medicine, led by researchers at the University […]
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