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The annual meeting of the American Society of Nephrology (Kidney Week) was held this year from Nov. 2 to 5 in Philadelphia and attracted participants from around the world, including nephrology specialists, researchers, scientists, and other health care professionals. The conference featured presentations focusing on the latest advances in the management of patients with kidney diseases and related disorders. In […]

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Study finds single dose of zilebesiran safely and effectively lowers blood pressure for six months

Compared to participants who received the placebo, participants who received single doses of zilebesiran had greater than 10 mm Hg reductions, on average, in 24-hour systolic blood pressure and greater than 90% reductions in serum levels of AGT, a hormone produced predominantly in the liver that contributes to blood pressure regulation. At the three-month follow-up, the participants in groups that […]

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Elderly Patients at Highest Risk for Severe COVID Outcomes

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. More than 40% of patients aged 80 years or older in the lower mainland of British Columbia remained uninfected by SARS-CoV-2 by July 2023, data indicate. These patients also were at highest risk for severe outcomes such as hospitalization or death. By the end of two […]

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There is a clear, unmet need for tolerable treatments that can produce durable remission among patients with higher-risk myelodysplastic syndromes (HR-MDS), according to a study published online Sept. 7 in Leukemia & Lymphoma. Shanna Arnold Egloff, Ph.D., from HCA Healthcare in Nashville, tofranil for nerve pain Tennessee, and colleagues describe clinical presentation, patient-related factors, prognostic characteristics, treatment patterns, clinical outcomes […]

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Researchers use AI to track chemotherapy complications, help families fighting pediatric cancer

In Mexico, where cancer is the second leading cause of death for children, families travel a significant distance to specialty hospitals for chemotherapy treatment. After each round of chemotherapy, children are typically sent home to recover. But when a patient leaves the hospital after treatment, there is no system to follow up on their recovery or outcome. Meanwhile, families are […]

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PTSD symptoms linked to higher carotid atherosclerosis in women

For midlife women, posttraumatic stress disorder (PTSD) symptoms are associated with higher carotid atherosclerosis and with greater brain small vessel disease and poorer cognitive performance among APOE ε4 carriers, according to a study published online Nov. 2 in JAMA Network Open. Rebecca C. Thurston, Ph.D., from the University of Pittsburgh, and colleagues examined whether PTSD symptoms among midlife women are […]

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Reviewed Neurodegenerative diseases like Alzheimer's and Parkinson's can be associated to depression and anxiety. Dr. Sabine Krabbe, a neuroscientist at DZNE's Bonn site, is receiving 1.2 million US dollars from the Chan Zuckerberg Initiative to understand the mechanisms involved in the onset of these syndromes. To this end, she aims to examine the function of the brain's "emotion center" using […]

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How a single synapse transmits both visual and subconscious information to the brain of fruit flies

Research led by Peking University, China, has discovered a single type of retinal photoreceptor cell in Drosophila (fruit fly) is involved in both visual perception and circadian photoentrainment by co-releasing histamine and acetylcholine at the first visual synapse. In a paper, “A single photoreceptor splits perception and entrainment by cotransmission,” published in Nature, the team details the discovery that the […]

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RIKEN geneticists have developed a tool that can quickly and accurately analyze variants in mobile genetic elements, commonly known as “jumping genes.” This promises to shed light on the role such variants play in disease. Most genes stay put within the genome, but a few have the ability to jump around and insert themselves in different locations. Known as mobile […]

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