Researchers at the University of Pittsburgh analyzed thousands of human genomes to find new gene variations responsible for controlling the levels of blood plasma molecules linked to Alzheimer’s disease risk. The findings, published recently in Molecular Psychiatry, could contribute to the future development of simple blood tests for the disease. Led by Ilyas Kamboh, Ph.D., professor of human genetics and […]
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Photo: Guy Friedman When Amazon Clinic spread out into all 50 states, SteadyMD was right there with it – or you might say within it. SteadyMD, which offers a B2B telehealth platform and nationwide clinician workforce, has been an important part of Amazon Clinic’s journey. The telehealth company worked with Amazon for months helping develop Amazon Clinic and was one […]
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In a recent study posted to the bioRxiv* preprint server, researchers used a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein-pseudotyped viral model to characterize SARS-CoV-2 BA.2.86 variant neutralization by monoclonal antibodies (mAbs) and by sera obtained from Stockholm, inclusive of a recent group, and another group sampled before the XBB variant emerged in Sweden. Study: Sensitivity of […]
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TOPLINE Biochemical recurrence (BCR) falls short as a reliable surrogate for overall survival in localized prostate cancer trials and may not be a suitable primary endpoint. METHODOLOGY In trials of localized prostate cancer, BCR remains a controversial surrogate endpoint for overall survival. The meta-analysis included 10,741 patients from 11 randomized clinical trials; the median follow-up was 9.2 years. Interventions included […]
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More than 1 billion people worldwide have obesity. About 28.5 million people globally have high cholesterol. Both conditions increase a person’s risk for other diseases such as cardiovascular disease and diabetes. Researchers from the University of Massachusetts Amherst have designed a nanogel-based carrier to deliver a drug that mimics synthetic thyroid hormone directly to the liver. Scientists found via a […]
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New research published in the Journal of the American Geriatrics Society indicates that antipsychotics are likely overprescribed and used inappropriately among patients with Alzheimer’s disease and related dementias (ADRD) receiving home health care, and such use is linked to worse patient outcomes. Antipsychotic drugs are not approved for the treatment of dementia—they are mostly used off-label to manage the symptoms […]
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In a study of US adolescents, both victims and perpetrators of cyberbullying were more likely than other youth to experience eating disorder symptoms. The findings are published in the International Journal of Eating Disorders. In the study of 10,258 adolescents aged 10–14 years, participants answered questions about whether they had experienced cyberbullying victimization and perpetration, as well as whether they […]
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The hyperactivity disorder, usually referred to as ADHD, is an independent risk factor for several common and serious mental health issues, finds research published in the open access journal BMJ Mental Health. It is associated with major depression, post traumatic stress disorder, the eating disorder anorexia nervosa, and suicide attempts, the findings show, prompting the researchers to recommend vigilance by […]
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A new multi-site study led by Indiana University School of Medicine has found increasing pediatric readiness in emergency departments reduces but does not eliminate racial and ethnic disparities in children and adolescents with acute medical emergencies. The study also involved researchers from Oregon Health and Science University and UC Davis Health. They recently published their findings in JAMA Open Network. […]
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Chronic kidney disease is a public health burden impacting more than 37 million people worldwide, including nearly one million Americans. It is characterized by the accumulation of toxins, which further damages the kidney, yet the mechanisms responsible for this phenomenon needs to be better understood. Researchers from Boston University Chobanian & Avedisian School of Medicine have discovered a novel protective […]
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