In search of the ‘inflammatory Achilles heel’

When our bodies become infected, various immune responses are triggered, starting with a release of granulocytes, white blood cells containing special enzymes that make up about half or more of all human white blood cells. Neutrophils are also granulocytes that fight off invasive bacteria and fungi, often with zero tolerance for such invaders. Sometimes, however, a balanced and less aggressive […]

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Envíos ilegales de medicamentos por correo no son de opioides. Muchos contienen Viagra genérico

Durante años, la Administración de Drogas y Alimentos de los Estados Unidos (FDA) ha defendido sus esfuerzos por interceptar los medicamentos con receta que llegan del extranjero por correo como necesarios para impedir la entrada de opioides peligrosos, como el fentanilo. La industria farmacéutica cita a menudo estas preocupaciones en su batalla para frenar las numerosas propuestas en Washington para […]

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Are self-sanitizing disinfectants containing quaternary ammonium compounds truly effective against respiratory viruses?

*Important notice: bioRxiv publishes preliminary scientific reports that are not peer-reviewed and, therefore, should not be regarded as conclusive, guide clinical practice/health-related behavior, or treated as established information. In a recent study posted to the bioRxiv* preprint server, researchers evaluated the antimicrobial efficiency of two commercially available disinfectants containing quaternary ammonium compounds against influenza A virus (hemagglutinin 1 neuraminidase 1 […]

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Doctor-Per-Capita Ratios Inadequate for Workforce Planning

Changing demographics and physician work trends need to be factored into workforce planning in Canada, moving beyond simple physician-to-population ratios, a new study suggests. In a data analysis, after the researchers adjusted for population aging and physicians’ declining work hours, a perceived increase in physicians per capita from 1987 to 2019 became a 4% reduction. Arthur Sweetman, PhD After that […]

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Antipsychotic Cuts Alzheimer’s-Related Agitation

The antipsychotic brexpiprazole effectively improves agitation associated with Alzheimer’s disease (AD) with favorable tolerability, results of a phase 3 study suggest. “In this phase 3 trial of patients with agitation in Alzheimer’s dementia, treatment with brexpiprazole 2 or 3 mg/d resulted in statistically significantly greater improvements in agitation versus placebo on the primary and key secondary endpoints,” said study investigator […]

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