Getting through the holidays with celiac disease

As I prepared for my women’s group Christmas cookie exchange, I realized how tough this season might be for someone with celiac disease. This condition can cause immense damage to the intestines when susceptible individuals consume gluten—a protein found in wheat, rye and barley. And holiday or not, a lot of foods contain gluten. Besides the obvious baked goods made […]

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Evolving insights in blood-based liquid biopsies for prostate cancer interrogation

A new research perspective was published in Oncoscience on November 30, 2023, titled, “Evolving insights in blood-based liquid biopsies for prostate cancer interrogation.” During the last decade, blood sampling of cancer patients aimed at analyzing the presence of cells, membrane-bound vesicles, or molecules released by primary tumors or metastatic growths emerged as an alternative to traditional tissue biopsies. The advent […]

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Engineers design a robotic replica of the hearts right chamber

MIT engineers have developed a robotic replica of the heart’s right ventricle, which mimics the beating and blood-pumping action of live hearts. The robo-ventricle combines real heart tissue with synthetic, balloon-like artificial muscles that enable scientists to control the ventricle’s contractions while observing how its natural valves and other intricate structures function. The artificial ventricle can be tuned to mimic […]

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Large language models enhance differential diagnosis, paving the way for AI-assisted medical decision-making

A recent study published in the ArXiv preprint* server discusses the optimization of large language models (LLMs) for accurate differential diagnosis (DDx). Study: Towards Accurate Differential Diagnosis with Large Language Models. Image Credit: novak.elcic / Shutterstock.com *Important notice: arXiv publishes preliminary scientific reports that are not peer-reviewed and, therefore, should not be regarded as conclusive, guide clinical practice/health-related behavior, or treated as […]

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BCMA+ EV levels correlate with myeloma response to belantamab-mafodotin

A new research paper was published in Oncotarget, entitled, “Plasma levels of BCMA-positive extracellular vesicles correlate to response and side effects in myeloma patients treated with belantamab-mafodotin.” In myeloma patients, high levels of soluble B-cell maturation antigen (sBCMA) can limit the efficacy of BCMA-directed therapies. Belantamab-mafodotin is a BCMA antibody-drug conjugate and shows good overall response rates in heavily pretreated […]

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