Researchers identify mechanisms of pregnancy-associated heart growth

Northwestern Medicine scientists have uncovered a key regulator of pregnancy-associated heart growth, according to a recent study published in the Journal of Clinical Investigation. An mRNA-regulating protein called ZFP36L2 is critical for ceasing this heart growth after the pregnancy has ended, according to Hossein Ardehali, MD, Ph.D., the Thomas D. Spies Professor of Cardiac Metabolism and senior author of the […]

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Researchers describe the regenerative potential of solid bone marrow aspirate concentrate

A new study compares the regenerative potential of blood/bone marrow aspirate concentrates obtained from arterial blood, venous blood, and bone marrow aspirate. The study, conducted in rabbits, is reported in the peer-reviewed journal Tissue Engineering Part A. Blood concentrate material such as platelet-rick fibrin (PRF) is used in clinical practice to promote tissue regeneration in the fields of dentistry, orthopedic […]

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While drug overdose deaths reached an all-time high in 2021, opioid prescribing by physicians and clinicians dropped significantly in emergency departments that prioritized personalized feedback between peers, according to a new analysis in Annals of Emergency Medicine. From January 2019 to July 2021, dog swim with pink eye medicine opioid prescribing dropped 35% among physicians and 41% among nurse practitioners […]

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Patients who receive parathyroidectomy for mild primary hyperparathyroidism show no benefits in survival or morbidity, including fractures, cancer, or cardiovascular outcomes over more than 10 years, wegman’s pharmacy formulary when compared with those not receiving the surgery, results from a randomized, prospective trial show. “In contrast to existing data showing increased mortality and cardiovascular morbidity in mild primary hyperparathyroidism, we […]

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US judge strikes down CDC mask mandate for public transport

A US federal judge on Monday struck down the COVID-19 mask mandate for public transportation imposed by the administration of President Joe Biden. US District Judge Kathryn Kimball Mizelle of the Middle District of Florida said the mask mandate exceeds the statutory authority of the Centers for Disease Control and Prevention (CDC). The mandate requiring face masks on airplanes, the […]

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Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. A federal judge in Florida has struck down the Biden administration’s mandate that travelers on airlines, buses, trains and other public transit wear masks. The mandate, enacted in February 2021, is unconstitutional because Congress never granted the CDC to power create such a requirement, U.S. District […]

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When the World Health Organization endorsed the world’s first malaria vaccine in October 2021, it was a pivotal moment in a very long quest. I was completely overwhelmed with emotion. I tweeted, emailed, texted and called colleagues, friends and family members. Some of us cried. This vaccine, which will be rolled out starting in 2022 is urgently needed. But it […]

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Novel CAR T Therapy for Solid Tumors: ‘Exciting Advance’

NEW ORLEANS — Chimeric antigen receptor T-cell (CAR T) therapy has achieved impressive outcomes in patients with hematologic cancers, but similar results for those with solid tumors have remained elusive. Now, a new CAR T construct that targets the tumor-specific antigen claudin 6 (CLDN6) is showing promising preliminary activity against relapsed or refractory advanced solid tumors, especially testicular and ovarian […]

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