High blood pressure: the Female immune system, protects against hypertension – Natural medicine naturopathic specialist portal
Why men frequently suffer from hypertension
The immune system of the woman produces anti-inflammatory T-cells that keep the blood pressure low. In contrast to men, women have an innate ability to protect itself from high blood pressure, as a recent study shows.
Research one of the causes that affects the end of the Medical College of Georgia at Augusta University decrypted why women less often from hypertension than men. The Team discovered that so-called Tregs in the blood of the subjects. These regulatory T-cells are T-helper cells to the immune system and keep the blood pressure low. Also in the case of pregnancies Tregs play an important role. The results of the study were recently published in the renowned scientific journal “Hypertension”.
Women produce specialized immune cells
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Men suffer more often from hypertension than women. Why this is so, was yet in Detail unclear. Now a recent study shows that women have an innate protection against hypertension in the cradle. Through the production of specialized T-cells (Treg) are you in a much better position to keep your pressure low, and to inhibit inflammation.
Tregs protect the fetus in the mother’s womb
It was already known that the Treg production increases during pregnancy. According to the researchers, this supports a healthy pregnancy. The T-cells ensure that the immune system of the woman attacks the fetus, since this also contains the DNA of the father, and thus as a foreign body to identify. Now showed that the same cells are also involved in the Regulation of blood pressure.
The multi-talent in the immune system of the woman
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The Tregs seem to be involved in excessive to prevent immune responses. Such so-called cytokine towers play even with heavy COVID-19-gradients, and immune diseases such as rheumatoid Arthritis an important role. Especially the most common death is, however, important to highlight that high blood pressure is seizures a major risk factor for heart disease and stroke – causes.
Tregs from the same more of a salt-rich diet
In a study in rats, the researchers showed that the female animals were in the situation, the effects of a salt rich diet attenuate. Male and female rats were given a high-salt diet, and blood pressure in both sexes, increase in the first two days of significant.
In the course of 21 days, the blood pressure of the female animals was significantly lower than the values of the male rats. The researchers were able to document that the females had significantly produced more blood pressure-lowering Tregs. This should not eat women, but to motivate more salt, because the kidney damage caused by salt-rich diet in rats, were in male and female animals the same.
Men and women seem to regulate blood pressure differently
When the scientists reduced scientists the number of Tregs in the females artificially increased the blood pressure by up to 40 percent and corresponded to the values of the males. As the Team reduced the number of Tregs in male rats, the blood pressure values are the same. “The fact that the decrease of Tregs had in men no impact on blood pressure, could indicate that the male blood pressure under normal conditions is so dependent on this mechanism,” says Dr. Jennifer C. Sullivan from the research team.
Potential new treatment for hypertension
“We are due to studies in this and other models of the opinion that the ability of the woman, these T-regulatory to maintain the cells, or highly regulate is crucial for their ability to lower blood pressure maintain,” says Dr. Sullivan. This will offer a new approach for the treatment of hypertension, especially in women.
Tregs as a therapy for chronic inflammatory diseases?
“If we can better understand how and why women increase their Tregs, this could lead to therapies that may be for both sexes to inflammation-rich States, such as autoimmune and cardiovascular diseases, or to treat,” says the scientist. First Trials with autologous Tregs therapy showed promising results in chronic inflammation diseases such as Crohn’s disease and type 1 Diabetes. (vb)
Read also: The blood pressure naturally lower.