Reactive arthritis is fueled by amyloid protein during salmonella infection

Like the infrastructure of an apartment building, a fibrous protein known as curli amyloid that is produced by bacteria provides the supportive framework for biofilms—thick extracellular substances made by bacteria that enable multiple bacterial cells to assemble, survive, and thrive together. Curli amyloid, however, is also a key factor in diarrheal illness brought about by bacterial infection, and its harmful […]

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Older, critically ill patients with COVID-19 may have increased risk of bradycardia with lopinavir and ritonavir

Older, critically ill patients with COVID-19 who received a combination of the antiretroviral medications lopinavir and ritonavir experienced bradycardia, a slow heart rate, more often, according to new research published today in Circulation: Arrhythmia and Electrophysiology, an American Heart Association journal. The combination of antiretroviral medications lopinavir (LPV) and ritonavir (RTV) have been previously used to treat patients with SARS-Cov-1 […]

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Amygdala changes in male patients with schizophrenia and bipolar disorder

Researchers at Kumamoto University, Japan have revealed that DNA methylation occurs in the gene that codes serotonin transporter (SERT), a protein that regulates neurotransmitter transmission, in schizophrenia and bipolar patients. Particularly prominent in males and patients with certain genetic polymorphisms, this methylation is inversely correlated with volume of the amygdala in the brain. This work is expected to lead to […]

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Scientists reveal comprehensive proteomic map of human lung adenocarcinoma

A team of Chinese scientists from the State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica under the Chinese Academy of Sciences, along with multi-institutional collaborators, has recently reported a comprehensive proteomic analysis based on 103 Chinese patients with lung adenocarcinoma (LUAD), a leading cause of death among all types of cancer worldwide. The research revealed LUAD-related molecular […]

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Schools or bars? Opening classrooms may mean hard choices

President Donald Trump insists that schools reopen this fall. Many parents, educators, doctors and economists want the same thing. But getting children back to school safely could mean keeping high-risk spots like bars and gyms closed. A growing chorus of public health experts is urging federal, state and local officials to reconsider how they are reopening the broader economy, and […]

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Menthol cigarette ban in the US may lower number of smokers

Extending the United States cigarette flavour ban to include menthol products could encourage existing smokers to quit and lower the rates of people starting to smoke, according to a study published in the open access journal BMC Public Health. Under the 2009 Family Smoking Prevention and Tobacco Control Act, the United States Food and Drug Administration (FDA) banned flavours in […]

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