Early predictions underestimated how long patients with COVID-19 would need to stay in hospitals and how many would require intensive care, according to a study looking at California and Washington state. A principal goal of physical distancing and lockdown measures during the COVID-19 pandemic is to prevent healthcare services from becoming overwhelmed. In the United States, policymakers had to rely […]
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By analyzing tumors from patients treated with immunotherapy for advanced kidney cancer in three clinical trials, Dana-Farber Cancer Institute scientists have identified several features of the tumors that influence their response to immune checkpoint inhibitor drugs. The research was presented during the Clinical Science Symposium at the American Society of Clinical Oncology (ASCO) Annual Meeting and published simultaneously in Nature […]
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(HealthDay)—Insulin infusion helps achieve glycemic targets and may reduce the risk for poor outcomes in patients with hyperglycemia and COVID-19, according to a study published online May 19 in Diabetes Care. Celestino Sardu, M.D., Ph.D., from University of Campania in Caserta, Italy, and colleagues examined the effects of optimal glycemic control in patients with hyperglycemia and COVID-19. The analysis included […]
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Argenx, a Belgian drug maker, recently announced a successful phase 3 ADAPT trial of its experimental drug, efgartigimod. The company plans to seek U.S. approval of the drug by the end of year as a potential new treatment for patients with generalized myasthenia gravis (gMG), a rare and chronic autoimmune disease where communication between nerves and muscles is disrupted, causing […]
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A team of researchers at Yale University (with assistance from the Connecticut Agricultural Experimental Station) has found early signs that testing wastewater for SARS-CoV-2 virus RNA can be used to gauge early COVID-19 infection rates in a given community. They have written a paper describing their findings and uploaded it to the medRxiv preprint server. Prior research has shown that […]
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With research laboratories around the world racing to develop a coronavirus vaccine, a unique challenge has emerged: how to balance intellectual property rights with serving the public good. Questions of patent protection and access to those patents has prompted an international group of scientists and lawyers to establish the Open COVID Pledge. This movement calls on organisations to freely make […]
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India’s coronavirus death toll passed neighbouring China’s on Friday, with 175 new fatalities in 24 hours taking the total to 4,706, according to official data. India, home to some of the world’s most packed cities and a creaking healthcare system, is emerging as a new hotspot with record jumps in new cases in recent days. Figures from India’s health ministry […]
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Two researchers at the University of Cincinnati College of Engineering and Applied Science have been granted funding from the National Science Foundation for a project with the goal of creating a heatable and reusable face mask for medical workers and others. “Currently, there is a significant shortage of personal protective equipment, particularly face masks, due to the COVID-19 pandemic in […]
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A cancer therapy may shrink the tumor of a patient, and the patient may feel better. But unseen on a CT scan or MR image, some of the cells are undergoing ominous changes. Fueled by new genetic changes due to cancer therapy itself, these rogue cells are becoming very large with twice or quadruple the number of chromosomes found in […]
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A Ludwig Cancer Research study has profiled, in a sweeping comparative analysis, the distinct immune landscapes of tumors that arise in the brain, or gliomas, and those that metastasize to the organ from the lungs, breast and skin. Led by Ludwig Lausanne Member Johanna Joyce and published in the current issue of Cell, the study captures in granular detail how […]
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